The role of growth and seasonal fat dynamics in the maturation of Atlantic salmon (Salmo salar) parr

Growth studies of individually tagged 1+ Atlantic salmon parr revealed no difference in specific growth rates between maturing and non-maturing male parr. However, maturing parr had lower mean condition factors than non- maturing males during March, and were characterized by greater increases in condition factor during April. Changes in condition factor during April were related to feeding opportunity during that month, and a relationship between April increases in condition factor and maturation rates of males was confirmed in 0 sibling populations of salmon parr. A relationship between condition factor increases during April and maturation in autumn was also confirmed for grilse and reconditioned kelts. Maturing male parr replenished non-mesenteric fat stores during April, and the mesenteric store in May. In comparison lipid replenishment and deposition in non-maturing fish was delayed until May and June respectively. The April increases in condition factor of maturing males are therefore symptomatic of the earlier replenishment of lipids depleted during winter. The mesenteric fat store is an important reserve utilized during maturation in male parr and contains up to 40% of the total lipid content of salmon parr. Its size decreases significantly during the later stages of gonadal development, while the relative size of females and non-maturing males's increases. Mesenteric fat levels are highest in maturing males in July, just before gonadal growth accelerates, and there is a strong correlation between GSI and mesenteric fat levels at this time. Because feeding in maturing male parr is depressed between August and October, the size of the mesenteric store is likely to be important in sustaining gonad differentiation, as well as in the elaboration of secondary sexual characters. Seasonal manipulations of growth rate resulted in variations in the maturation rate of male parr. Increased feeding and growth during April and May increased maturation rates whereas decreased feeding resulted in delayed replenishment of fat reserves and lower maturation rates compared with controls. Changes in growth during other months had little effect on maturation rates. The results indicate that maturation is initiated in a proportion of male parr as early as in winter, but is suppressed if fat deposition into the mesenteric store is below a genetically determined level by the end of May. However, the timing of fat deposition into the mesenteric store is dependendant on the prior replenishment of other body stores, and so is particularly sensitive to fat dynamics in April. The manipulation of maturation rates by altering growth opportunity in April and May occurs despite the fact that physiological changes leading to maturation are already in train. Thus maturation is switched off in many male parr by reduced feeding and growth during spring months. This maturation suppression switch, related to growth in fat reserves during spring months, provides the means by which growth exerts some control over maturation, and is likely to be responsible for much of the correlation between fast growth and early age of maturation in salmonids. The switch is time specific and is believed to be adaptive. It is likely to prevent maturation in the autumn if the winter is long and spring is late. A late spring shortens the growing season, and the probability of acquiring sufficient fat reserves for successful spawning and overwintering would be low in such summers. The physiological mechanisms by which growth in fat reserves during spring could affect maturation are discussed, and a hypothetical model for the role of fat stores in the hormonal control of maturation, is presented

Toward Intelligent Support of Authoring Machinima Media Content: Story and Visualization

The Internet and the availability of authoring tools have enabled a greater community of media content creators, including nonexperts. However, while media authoring tools often make it technically feasible to generate, edit and share digital media artifacts, they do not guarantee that the works will be valuable or meaningful to the community at large. Therefore intelligent tools that support the authoring and creative processes are especially valuable. In this paper, we describe two intelligent support tools for the authoring and production of machinima. Machinima is a technique for producing computer-animated movies through the manipulation of computer game technologies. The first system we describe, ReQUEST, is an intelligent support tool for the authoring of plots. The second system, Cambot, produces machinima from a pre-authored script by manipulating virtual avatars and a virtual camera in a 3D graphical environment

Women's sport and media : a call to critical arms

After many years of struggle, women's sport is experiencing an upsurge around the world. This advance means, given the co-dependent relationship between sport and media, greater coverage of women's sport. These are positive developments regarding gender equality, especially given the socio-cultural power of the "media sports cultural complex". It is important, though, not to exaggerate the institutional success of women's sport and media that has begun from a low base and encounters continued resistance. Improvements are also globally uneven, being more evident among relatively affluent, culturally advantaged communities, especially in the West, with compounding intersectional disadvantage for women in poorer, racialized and religiously oppressive contexts. Where successes have been achieved, they should be subject to the same kind of critical scepticism applying to wider sport and media-related issues such as the environment, "sportswashing", sport diplomacy, capitalist exploitation, and challenges to sport's traditional binary gender order. This article, while noting an increase in feminist media research and scholarship applied to sport, argues that it is still under-represented in communication and media studies. It constitutes a call to this field for greater analytically reflexive attention to an area of popular culture that consumes enormous media space in a critical cultural-political moment

Review of best management practices for aquatic vegetation control in stormwater ponds, wetlands, and lakes

Auckland Council (AC) is responsible for the development and operation of a stormwater network across the region to avert risks to citizens and the environment. Within this stormwater network, aquatic vegetation (including plants, unicellular and filamentous algae) can have both a positive and negative role in stormwater management and water quality treatment. The situations where management is needed to control aquatic vegetation are not always clear, and an inability to identify effective, feasible and economical control options may constrain management initiatives. AC (Infrastructure and Technical Services, Stormwater) commissioned this technical report to provide information for decision- making on aquatic vegetation management with in stormwater systems that are likely to experience vegetation-related issues. Information was collated from a comprehensive literature review, augmented by knowledge held by the authors. This review identified a wide range of management practices that could be potentially employed. It also demonstrated complexities and uncertainties relating to these options that makes the identification of a best management practice difficult. Hence, the focus of this report was to enable users to screen for potential options, and use reference material provided on each option to confirm the best practice to employ for each situation. The report identifies factors to define whether there is an aquatic vegetation problem (Section 3.0), and emphasises the need for agreed management goals for control (e.g. reduction, mitigation, containment, eradication). Resources to screen which management option(s) to employ are provided (Section 4.0), relating to the target aquatic vegetation, likely applicability of options to the system being managed, indicative cost, and ease of implementation. Initial screening allows users to shortlist potential control options for further reference (Section 5.0). Thirty-five control options are described (Section 5.0) in sufficient detail to consider applicability to individual sites and species. These options are grouped under categories of biological, chemical or physical control. Biological control options involve the use of organisms to predate, infect or control vegetation growth (e.g. classical biological control) or manipulate conditions to control algal growth (e.g. pest fish removal, microbial products). Chemical control options involve the use of pesticides and chemicals (e.g. glyphosate, diquat), or the use of flocculants and nutrient inactivation products that are used to reduce nutrient loading, thereby decreasing algal growth. Physical control options involve removing vegetation or algal biomass (e.g. mechanical or manual harvesting), or setting up barriers to their growth (e.g. shading, bottom lining, sediment capping). Preventative management options are usually the most cost effective, and these are also briefly described (Section 6.0). For example, the use of hygiene or quarantine protocols can reduce weed introductions or spread. Catchment- based practices to reduce sediment and nutrient sources to stormwater are likely to assist in the avoidance of algal and possibly aquatic plant problems. Nutrient removal may be a co-benefit where harvesting of submerged weed biomass is undertaken in stormwater systems. It should also be considered that removal of substantial amounts of submerged vegetation may result in a sudden and difficult-to-reverse s witch to a turbid, phytoplankton dominated state. Another possible solution is the conversion of systems that experience aquatic vegetation issues, to systems that are less likely to experience issues. The focus of this report is on systems that receive significant stormwater inputs, i.e. constructed bodies, including ponds, amenity lakes, wetlands, and highly-modified receiving bodies. However, some information will have application to other natural water bodies

Kepler Observations of Transiting Hot Compact Objects

Kepler photometry has revealed two unusual transiting companions orbiting an early A-star and a late B-star. In both cases the occultation of the companion is deeper than the transit. The occultation and transit with follow-up optical spectroscopy reveal a 9400 K early A-star, KOI-74 (KIC 6889235), with a companion in a 5.2 day orbit with a radius of 0.08 Rsun and a 10000 K late B-star KOI-81 (KIC 8823868) that has a companion in a 24 day orbit with a radius of 0.2 Rsun. We infer a temperature of 12250 K for KOI-74b and 13500 K for KOI-81b. We present 43 days of high duty cycle, 30 minute cadence photometry, with models demonstrating the intriguing properties of these object, and speculate on their nature.Comment: 12 pages, 3 figures, submitted to ApJL (updated to correct KOI74 lightcurve

Optical and transport properties of heavy fermions: theory compared to experiment

Employing a local moment approach to the periodic Anderson model within the framework of dynamical mean-field theory, direct comparison is made between theory and experiment for the dc transport and optical conductivities of paramagnetic heavy fermion and intermediate valence metals. Four materials, exhibiting a diverse range of behaviour in their transport/optics, are analysed in detail: CeB6, YbAl3, CeAl3 and CeCoIn5. Good agreement between theory and experiment is in general found, even quantitatively, and a mutually consistent picture of transport and optics results.Comment: 21 pages, 10 figures; Replacement with minor style changes made to avoid postscript file error

Discovery of the Transiting Planet Kepler-5B

We present 44 days of high duty cycle, ultra precise photometry of the 13th magnitude star Kepler-5 (KIC 8191672, T(eff) = 6300 K, log g = 4.1), which exhibits periodic transits with a depth of 0.7%. Detailed modeling of the transit is consistent with a planetary companion with an orbital period of 3.548460 +/- 0.000032 days and a radius of 1.431(-0.052)(+0.041) R(J). Follow-up radial velocity measurements with the Keck HIRES spectrograph on nine separate nights demonstrate that the planet is more than twice as massive as Jupiter with a mass of 2.114(-0.059)(+0.056) M(J) and a mean density of 0.894 +/- 0.079 g cm(-3).NASA's Science Mission DirectorateAstronom

Ks-band detection of thermal emission and color constraints to CoRoT-1b: A low-albedo planet with inefficient atmospheric energy redistribution and a temperature inversion

We report the detection in Ks-band of the secondary eclipse of the hot Jupiter CoRoT-1b, from time series photometry with the ARC 3.5-m telescope at Apache Point Observatory. The eclipse shows a depth of 0.336+/-0.042 percent and is centered at phase 0.5022 (+0.0023,-0.0027), consistent with a zero eccentricity orbit ecos{\omega} = 0.0035 (+0.0036,-0.0042). We perform the first optical to near-infrared multi-band photometric analysis of an exoplanet's atmosphere and constrain the reflected and thermal emissions by combining our result with the recent 0.6, 0.71, and 2.09 micron secondary eclipse detections by Snellen et al. (2009), Gillon et al. (2009), and Alonso et al. (2009a). Comparing the multi-wavelength detections to state-of-the-art radiative-convective chemical-equilibrium atmosphere models, we find the near-infrared fluxes difficult to reproduce. The closest blackbody-based and physical models provide the following atmosphere parameters: a temperature T = 2454 (+84,-170) K, a very low Bond albedo A_B = 0.000 (+0.087,-0.000), and an energy redistribution parameter P_n = 0.1, indicating a small but nonzero amount of heat transfer from the day- to night-side. The best physical model suggests a thermal inversion layer with an extra optical absorber of opacity kappa_e =0.05cm^2g^-1, placed near the 0.1-bar atmospheric pressure level. This inversion layer is located ten times deeper in the atmosphere than the absorbers used in models to fit mid-infrared Spitzer detections of other irradiated hot Jupiters.Comment: accepted for publication on Ap

Novel TNF Receptor-1 Inhibitors Identified as Potential Therapeutic Candidates for Traumatic Brain Injury

Background: Traumatic brain injury (TBI) begins with the application of mechanical force to the head or brain, which initiates systemic and cellular processes that are hallmarks of the disease. The pathological cascade of secondary injury processes, including inflammation, can exacerbate brain injury-induced morbidities and thus represents a plausible target for pharmaceutical therapies. We have pioneered research on post-traumatic sleep, identifying that injury-induced sleep lasting for 6 h in brain-injured mice coincides with increased cortical levels of inflammatory cytokines, including tumor necrosis factor (TNF). Here, we apply post-traumatic sleep as a physiological bio-indicator of inflammation. We hypothesized the efficacy of novel TNF receptor (TNF-R) inhibitors could be screened using post-traumatic sleep and that these novel compounds would improve functional recovery following diffuse TBI in the mouse. Methods: Three inhibitors of TNF-R activation were synthesized based on the structure of previously reported TNF CIAM inhibitor F002, which lodges into a defined TNFR1 cavity at the TNF-binding interface, and screened for in vitro efficacy of TNF pathway inhibition (IκB phosphorylation). Compounds were screened for in vivo efficacy in modulating post-traumatic sleep. Compounds were then tested for efficacy in improving functional recovery and verification of cellular mechanism. Results: Brain-injured mice treated with Compound 7 (C7) or SGT11 slept significantly less than those treated with vehicle, suggesting a therapeutic potential to target neuroinflammation. SGT11 restored cognitive, sensorimotor, and neurological function. C7 and SGT11 significantly decreased cortical inflammatory cytokines 3 h post-TBI. Conclusions: Using sleep as a bio-indicator of TNF-R-dependent neuroinflammation, we identified C7 and SGT11 as potential therapeutic candidates for TBI

Epidemiology of Pediatric Traumatic Brain Injury and Hypothalamic-Pituitary Disorders in Arizona

Traumatic brain injury (TBI) in children can result in long-lasting social, cognitive, and neurological impairments. In adults, TBI can lead to endocrinopathies (endocrine system disorders), but this is infrequently reported in children. Untreated endocrinopathies can elevate risks of subsequent health issues, such that early detection in pediatric TBI survivors can initiate clinical interventions. To understand the risk of endocrinopathies following pediatric TBI, we identified patients who had experienced a TBI and subsequently developed a new-onset hypothalamic regulated endocrinopathy (n = 498). We hypothesized that pediatric patients who were diagnosed with a TBI were at higher risk of being diagnosed with a central endocrinopathy than those without a prior diagnosis of TBI. In our epidemiological assessment, we identified pediatric patients enrolled in the Arizona Health Care Cost Containment System (AHCCCS) from 2008 to 2014 who were diagnosed with one of 330 TBI International Classification of Diseases (ICD)-9 codes and subsequently diagnosed with one of 14 central endocrinopathy ICD-9 codes. Additionally, the ICD-9 code data from over 600,000 Arizona pediatric patients afforded an estimate of the incidence, prevalence, relative risk, odds ratio, and number needed to harm, regarding the development of a central endocrinopathy after sustaining a TBI in Arizona Medicaid pediatric patients. Children with a TBI diagnosis had 3.22 times the risk of a subsequent central endocrine diagnosis compared with the general population (±0.28). Pediatric AHCCCS patients with a central endocrine diagnosis had 3.2-fold higher odds of a history of a TBI diagnosis than those without an endocrine diagnosis (±0.29). Furthermore, the number of patients with a TBI diagnosis for one patient to receive a diagnosis of a central endocrine diagnosis was 151.2 (±6.12). Female subjects were more likely to present with a central endocrine diagnosis after a TBI diagnosis compared to male subjects (64.1 vs. 35.9%). These results are the first state-wide epidemiological study conducted to determine the risk of developing a hypothalamic-pituitary disorder after a TBI in the pediatric population. Our results contribute to a body of knowledge demonstrating a TBI etiology for idiopathic endocrine disorders, and thus advise physicians with regard to TBI follow-up care that includes preventive screening for endocrine disorders.Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]